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SASInstitute A00-282 Exam Syllabus Topics:

SectionObjectives
Regulatory and Clinical Research Concepts- Clinical trial workflow
  • 1. Regulatory submission basics
    • 2. Study design fundamentals
      Clinical Trials Data Standards- CDISC Standards
      • 1. SDTM structure and implementation
        • 2. ADaM datasets and analysis-ready data
          SAS Programming for Clinical Trials- Reporting and Analysis
          • 1. Listings, tables, and figures generation
            • 2. Statistical reporting with SAS procedures
              - Data Management
              • 1. Dataset merging and manipulation
                • 2. Data cleaning and transformation

                  SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

                  Question 1

                  Given the data set RAWBP that is sorted by SUBJECT TEST WEEK:

                  Baseline is defined as the week 0 value. Your colleague provides the following SAS program to calculate change from baseline:
                  data bp;
                  set rawbp;
                  by subject test week;
                  retain baseline;
                  if first.subject then baseline = value;
                  if week > 0 then change = value - baseline;
                  run;
                  What does the code calculate as the change from baseline for systolic blood pressure (SBP) at week 3?

                  A. 40
                  B. -40
                  C. 30
                  D. -30


                  Question 2

                  A SAS report procedure results in the log below.

                  What should you add to the PROC REPORT to address the blue note in this log?

                  A. Use DEFINE statements with the WIDTH= option set large enough to print all values for each variable
                  B. Specify COLWIDTH= option with a value large enough to print all values in the data
                  C. Use DEFINE statements where FLOW is specified for each numeric variable
                  D. Use a FORMAT statement with formats large enough to print all values for each numeric variable


                  Question 3

                  The VISIT data set is multiple records per subject, sorted by usubjid vistdtc vistm and contains the following variables:

                  The DEATH data set is one record per subject, sorted by usubjid vistdtc vistm and contains the following variables:

                  Which program will combine the DEATH and VISIT data sets by matching records?

                  A. data data_1;
                  set death visit;
                  by usubjid vistdtc vistm;
                  run;
                  B. data data_1;
                  merge death visit;
                  by usubjid vistdtc vistm;
                  run;
                  C. data data_1;
                  merge death visit;
                  by usubjid vistm vistdtc;
                  run;
                  D. data data_1;
                  merge death visit;
                  run;


                  Question 4

                  The following SAS program is submitted:

                  What is the value of the variable day when the data step completes?

                  A. 8
                  B. 7
                  C. 6
                  D. 1


                  Question 5

                  Given the SAS data set containing subject's phone numbers

                  What is the value of PHONE2 for subject 005?

                  A. 2156319494
                  B. (215) 6319494
                  C. (215) 631-9494
                  D. 631-9494


                  Solutions:

                  Question 1
                  Answer: C
                  Question 2
                  Answer: D
                  Question 3
                  Answer: B
                  Question 4
                  Answer: A
                  Question 5
                  Answer: A

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