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ACRP ACRP-CP Exam Syllabus Topics:

SectionObjectives
Topic 1: Regulatory Compliance- Regulatory documentation and submissions
- Audit and inspection readiness
Topic 2: Data and Quality Management- Clinical data management principles
- Quality assurance and quality control
Topic 3: Clinical Research Foundations- Ethical conduct in clinical trials
- Good Clinical Practice (GCP) principles
Topic 4: Participant Safety and Protection- Safety reporting and adverse events
- Informed consent process
Topic 5: Study Operations- Study conduct and oversight
- Study planning and initiation

ACRP Certified Professional Sample Questions:

In order to conduct open-label, parallel group clinical trials according to sound scientific principles, which of the following design elements should be included?

  • A. Randomization
  • B. Privacy controls
  • C. Blinding
  • D. Placebo-controlled
Reveal Solution  Discussion  0

Correct Answer: A  🗳️

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SAEs must be reported immediately by the site to the:

  • A. Regulatory agency.
  • B. IRB/IEC.
  • C. DSMB/IDMC.
  • D. Sponsor.
Reveal Solution  Discussion  0

Correct Answer: D  🗳️

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A trial subject was involved in a traffic accident. The emergency room (ER) doctor notifies the investigator that he wants to give the subject a blood transfusion. Blood transfusion is one of the prohibited treatments in the trial. How should the investigator respond?

  • A. Ask the ER doctor not to transfuse blood and consider another treatment compliant with the protocol.
  • B. Advise the ER doctor to transfuse blood, and the PI should withdraw the subject from the trial.
  • C. Advise the ER doctor to transfuse the blood, and the PI should report this incident to the sponsor.
  • D. Report this incident immediately to the sponsor and leave the treatment decision to them.
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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A Phase I drug trial has been completed and preparations are being made to proceed to a Phase II trial. Who is responsible for revising the IB with this updated information?

  • A. DSMB/IDMC
  • B. Investigator
  • C. Sponsor
  • D. Health authority
Reveal Solution  Discussion  0

Correct Answer: C  🗳️

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When assessing the monitoring needs for a study, sponsors should:

  • A. Ensure monitoring visits are conducted at periodic intervals with a minimum of monthly monitoring visits.
  • B. Ensure monitors have the scientific and/or clinical knowledge needed to monitor the trial adequately.
  • C. Use central monitoring instead of conducting physical monitoring visits at sites.
  • D. Permit PIs to select a monitor for their site as long as they are independent of the PI.
Reveal Solution  Discussion  0

Correct Answer: B  🗳️

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